Elisabeth de St. Michel is born at Bideford, Devon, to Dorothea (b. 1609, d. in or after 1674), widow of Thomas Fleetwood of Cork and daughter of the prominent Hampshire landowner Sir Francis Kingsmill, and Alexandre le Marchant de St. Michel (d. 1672), a descendant of a distinguished Anjou family.
Marries Samuel Pepys in an unrecorded religious ceremony. This is the date Pepys identifies as their anniversary in his diary. Elisabeth is fifteen years of age; Samuel is twenty-two.
Marries Samuel Pepys at a civil service at St. Margaret's, Westminster. Elisabeth is described as being of St. Martin-in-the-Fields. In the early months of their marriage they live Samuel's attic apartment at Whitehall Palace.
Within a year of their marriage, Elisabeth leaves Whitehall to stay with her family at Charing Cross.
Returns to Whitehall in December 1657.
Samuel and Elisabeth move to a house in Axe Yard, Westminster.
Samuel and Elisabeth move to to the Navy Office at Seething Lane.
In June 1669 Pepys accompanies her husband and brother on a tour of northern France and the Netherlands where she contracts a fever, probably typhoid. She dies, age 29, at Seething Lane on 10 November, and is buried on 13 November in the chancel of St. Olave's Church, Westminster.